A common bean truncated CRINKLY4 kinase controls gene-for-gene resistance to the fungus <i>Colletotrichum lindemuthianum</i>

Abstract Identifying the molecular basis of resistance to pathogens is critical promote a chemical-free cropping system. In plants, nucleotide-binding leucine-rich repeat constitute largest family disease (R) genes, but this can be rapidly overcome by pathogen, prompting research into alternative sources resistance. Anthracnose, caused fungus Colletotrichum lindemuthianum, one most important diseases common bean. This study aimed identify Co-x, an anthracnose R gene conferring total extremely virulent C. lindemuthianum strain 100. To that end, we sequenced Co-x 58 kb target region in resistant JaloEEP558 (Co-x) bean and identified KTR2/3, additional encoding truncated chimeric CRINKLY4 kinase, located within kinase cluster. The presence KTR2/3 strictly correlated with 100 diversity panel beans. Furthermore, expression up-regulated 24 hours post-inoculation its transient susceptible genotype increases Our results provide evidence encodes probably resulting from unequal recombination event occurred recently Andean domesticated pool. atypical may act as decoy involved indirect recognition fungal effector.